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H. pylori is difficult to eradicate from the stomach because it is capable of developing resistance to commonly used antibiotics. Therefore, two or more antibiotics usually are given together with a PPI and/or bismuth containing compounds to eradicate the bacterium.

 

 

HELICOBACTER PYLORI BACTERIA


Helicobacter pylori (H. pylori) is a spiral-shaped bacterium (germ) that causes chronic inflammation (gastritis) and peptic ulcer disease (sores on the lining of the stomach or small intestine) in humans. It lives on the gastric epithelium under the mucus layer of stomach and duodenum (section of intestine just below stomach. The bacterium is thought to damage this mucus layer which is the stomach and duodenum's natural protection from gastric acids. Local inflammation caused by the bacterial infection and exposure to these acids can damage the lining of the stomach and duodenum, eventually leading to ulceration and possibly gastric cancer.

The bacterium was first discovered in 1982 by two Australian scientists Robin Warren and Barry Marshall. This bacteria is the most common cause of ulcers worldwide. Approximately half of the world's population is infected with H. pylori, which produces free radicals. The World Health Organisation has declared h'pylori as a carcinogen causing infected people to contract gastritis, stomach ulcers, colon and gastric cancer.

Right now, there is no vaccine against H. pylori. Although research suggests that infection is passed from person to person, exactly how this happens is not really known. Because transmission is not clearly understood, prevention guidelines are not yet available. With prolonged antibiotic therapy, H. pylori gastritis and peptic ulcer disease (especially ulcers in the duodenum, a portion of the small intestine) can often be cured.

Biaxin is one of the strongest antibiotic used to treat h.pylori infection, but it has been found to become antibiotic resistant. Besides killing bacteria, antibiotics also kill normal healthy cells.

H. pylori infection can be diagnosed with a blood test. Your doctor might also want you to get an x-ray or have endoscopy (an endoscope is a thin tube that carries a tiny camera) to see if you have an ulcer. A urea breath test is another way to find out if you have H. pylori infection.

Once a person is infected, the organism can live in the stomach indefinitely and may not cause clinical illness until many years later. There is a general consensus among doctors that patients should be treated if they are infected with H.pylori and have ulcers. The goal of treatment is to eradicate the bacteria, heal the ulcers, and prevent the ulcers' return.

OPTIVIN™ 's ability to inhibit the growth of H. pylori has been evaluated and backed by the first published study of various berry extracts against this bacteria.